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Phenotypic similarities between late-onset autosomal dominant and sporadic Alzheimer disease: A single-family case-control study
IMPORTANCE: The “amyloid hypothesis” posits that disrupted amyloid-beta (Aβ) homeostasis initiates the pathological process resulting in Alzheimer disease (AD). Autosomal dominant Alzheimer disease (ADAD) has an early symptomatic onset and is caused by single gene mutations that result in overproduc...
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| izdano v: | JAMA Neurol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025942/ https://ncbi.nlm.nih.gov/pubmed/27454811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.1236 |
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