Nalaganje...

Phenotypic similarities between late-onset autosomal dominant and sporadic Alzheimer disease: A single-family case-control study

IMPORTANCE: The “amyloid hypothesis” posits that disrupted amyloid-beta (Aβ) homeostasis initiates the pathological process resulting in Alzheimer disease (AD). Autosomal dominant Alzheimer disease (ADAD) has an early symptomatic onset and is caused by single gene mutations that result in overproduc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:JAMA Neurol
Main Authors: Day, Gregory S, Musiek, Erik S, Roe, Catherine M, Norton, Joanne, Goate, Alison M, Cruchaga, Carlos, Cairns, Nigel J, Morris, John C
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025942/
https://ncbi.nlm.nih.gov/pubmed/27454811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.1236
Oznake: Označite
Brez oznak, prvi označite!