Molecular classification of grade 3 endometrioid endometrial cancers identifies distinct prognostic subgroups

Our aim was to investigate whether molecular classification can be used to refine prognosis in grade 3 endometrioid endometrial carcinomas (EECs). Grade 3 EECs were classified into four subgroups: p53-abnormal, based on mutant-like immunostaining (p53abn); MMR-deficient, based on loss of mismatch re...

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Pubblicato in:Am J Surg Pathol
Autori principali: Bosse, Tjalling, Nout, Remi A., McAlpine, Jessica N., McConechy, Melissa K., Britton, Heidi, Hussein, Yaser, Gonzalez, Carlene, Ganesan, Raji, Steele, Jane C., Harrison, Beth T., Oliva, Esther, Vidal, August, Matias-Guiu, Xavier, Abu-Rustum, Nadeem R., Levine, Douglas A., Gilks, C. Blake, Soslow, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893364/
https://ncbi.nlm.nih.gov/pubmed/29505428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001020
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