Prenatal Exposure to Nitrosatable Drugs, Vitamin C, and Risk of Selected Birth Defects

BACKGROUND: Nitrosatable drugs, such as secondary or tertiary amines and amides react with nitrite in an acidic environment to form N-nitroso compounds, teratogens in animal models. Vitamin C is a known nitrosation inhibitor. METHODS: Using data from the National Birth Defects Prevention Study, we a...

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Bibliografiske detaljer
Udgivet i:Birth Defects Res A Clin Mol Teratol
Main Authors: Shinde, Mayura U., Vuong, Ann M., Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Huber, John C., Sharkey, Joseph R., Zheng, Qi, Suarez, Lucina, Langlois, Peter H., Canfield, Mark A., Romitti, Paul A., Malik, Sadia
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893146/
https://ncbi.nlm.nih.gov/pubmed/23716465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23137
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