Prenatal Exposure to Nitrosatable Drugs, Vitamin C, and Risk of Selected Birth Defects

BACKGROUND: Nitrosatable drugs, such as secondary or tertiary amines and amides react with nitrite in an acidic environment to form N-nitroso compounds, teratogens in animal models. Vitamin C is a known nitrosation inhibitor. METHODS: Using data from the National Birth Defects Prevention Study, we a...

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Vydáno v:Birth Defects Res A Clin Mol Teratol
Hlavní autoři: Shinde, Mayura U., Vuong, Ann M., Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Huber, John C., Sharkey, Joseph R., Zheng, Qi, Suarez, Lucina, Langlois, Peter H., Canfield, Mark A., Romitti, Paul A., Malik, Sadia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893146/
https://ncbi.nlm.nih.gov/pubmed/23716465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23137
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