Prenatal Exposure to Nitrosatable Drugs, Vitamin C, and Risk of Selected Birth Defects

BACKGROUND: Nitrosatable drugs, such as secondary or tertiary amines and amides react with nitrite in an acidic environment to form N-nitroso compounds, teratogens in animal models. Vitamin C is a known nitrosation inhibitor. METHODS: Using data from the National Birth Defects Prevention Study, we a...

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Detalhes bibliográficos
Publicado no:Birth Defects Res A Clin Mol Teratol
Main Authors: Shinde, Mayura U., Vuong, Ann M., Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Huber, John C., Sharkey, Joseph R., Zheng, Qi, Suarez, Lucina, Langlois, Peter H., Canfield, Mark A., Romitti, Paul A., Malik, Sadia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893146/
https://ncbi.nlm.nih.gov/pubmed/23716465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23137
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