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Prenatal Exposure to Nitrosatable Drugs, Vitamin C, and Risk of Selected Birth Defects

BACKGROUND: Nitrosatable drugs, such as secondary or tertiary amines and amides react with nitrite in an acidic environment to form N-nitroso compounds, teratogens in animal models. Vitamin C is a known nitrosation inhibitor. METHODS: Using data from the National Birth Defects Prevention Study, we a...

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Bibliografische gegevens
Gepubliceerd in:Birth Defects Res A Clin Mol Teratol
Hoofdauteurs: Shinde, Mayura U., Vuong, Ann M., Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Huber, John C., Sharkey, Joseph R., Zheng, Qi, Suarez, Lucina, Langlois, Peter H., Canfield, Mark A., Romitti, Paul A., Malik, Sadia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893146/
https://ncbi.nlm.nih.gov/pubmed/23716465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23137
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