Prenatal Exposure to Nitrosatable Drugs, Vitamin C, and Risk of Selected Birth Defects

BACKGROUND: Nitrosatable drugs, such as secondary or tertiary amines and amides react with nitrite in an acidic environment to form N-nitroso compounds, teratogens in animal models. Vitamin C is a known nitrosation inhibitor. METHODS: Using data from the National Birth Defects Prevention Study, we a...

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Publicado en:Birth Defects Res A Clin Mol Teratol
Main Authors: Shinde, Mayura U., Vuong, Ann M., Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Huber, John C., Sharkey, Joseph R., Zheng, Qi, Suarez, Lucina, Langlois, Peter H., Canfield, Mark A., Romitti, Paul A., Malik, Sadia
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893146/
https://ncbi.nlm.nih.gov/pubmed/23716465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23137
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