Dimeric IgG complexes from IVIg are incapable of inducing in vitro neutrophil degranulation or complement activation

PURPOSE: Intravenous immunoglobulin (IVIg) products contain various amounts of dimeric IgG complexes. Current insights into the possible biological activities of these dimers remain controversial, and both immunemodulating and immune-activating effects have been reported. Here, we analyzed the putat...

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Опубликовано в: :PLoS One
Главные авторы: Kustiawan, Iwan, Derksen, Ninotska I. L., Guhr, Theresa, Kruithof, Simone, Jiskoot, Wim, Vidarsson, Gestur, Rispens, Theo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892932/
https://ncbi.nlm.nih.gov/pubmed/29634774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195729
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