Enrichment of Sialylated IgG by Lectin Fractionation Does Not Enhance the Efficacy of Immunoglobulin G in a Murine Model of Immune Thrombocytopenia

Intravenous immunoglobulin G (IVIg) is widely used against a range of clinical symptoms. For its use in immune modulating therapies such as treatment of immune thrombocytopenic purpura high doses of IVIg are required. It has been suggested that only a fraction of IVIg causes this anti immune modulat...

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Main Authors: Guhr, Theresa, Bloem, Judith, Derksen, Ninotska I. L., Wuhrer, Manfred, Koenderman, Anky H. L., Aalberse, Rob C., Rispens, Theo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121734/
https://ncbi.nlm.nih.gov/pubmed/21731683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021246
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