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Dopaminergic neurotoxins induce cell death by attenuating NF-κB–mediated regulation of TRPC1 expression and autophagy

Alterations in Ca(2+) homeostasis affect neuronal survival. However, the identity of Ca(2+) channels and the mechanisms underlying neurotoxin-induced neuronal degeneration are not well understood. In this study, the dopaminergic neurotoxins 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenylpyridium io...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:FASEB J
मुख्य लेखकों: Sukumaran, Pramod, Sun, Yuyang, Antonson, Neil, Singh, Brij B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Federation of American Societies for Experimental Biology 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892723/
https://ncbi.nlm.nih.gov/pubmed/29150520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700662RR
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