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Preclinical characterization of anlotinib, a highly potent and selective vascular endothelial growth factor receptor‐2 inhibitor

Abrogating tumor angiogenesis by inhibiting vascular endothelial growth factor receptor‐2 (VEGFR2) has been established as a therapeutic strategy for treating cancer. However, because of their low selectivity, most small molecule inhibitors of VEGFR2 tyrosine kinase show unexpected adverse effects a...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Xie, Chengying, Wan, Xiaozhe, Quan, Haitian, Zheng, Mingyue, Fu, Li, Li, Yun, Lou, Liguang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891194/
https://ncbi.nlm.nih.gov/pubmed/29446853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13536
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