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Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans

It has long been suspected that the rate of mutation varies across the human genome at a large scale based on the divergence between humans and other species. However, it is now possible to directly investigate this question using the large number of de novo mutations (DNMs) that have been discovere...

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Pubblicato in:PLoS Genet
Autori principali: Smith, Thomas C. A., Arndt, Peter F., Eyre-Walker, Adam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891062/
https://ncbi.nlm.nih.gov/pubmed/29590096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007254
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