Characterization of a novel OTX2‐driven stem cell program in Group 3 and Group 4 medulloblastoma

Medulloblastoma (MB) is the most common malignant primary pediatric brain cancer. Among the most aggressive subtypes, Group 3 and Group 4 originate from stem/progenitor cells, frequently metastasize, and often display the worst prognosis, yet we know the least about the molecular mechanisms driving...

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Vydáno v:Mol Oncol
Hlavní autoři: Stromecki, Margaret, Tatari, Nazanin, Morrison, Ludivine Coudière, Kaur, Ravinder, Zagozewski, Jamie, Palidwor, Gareth, Ramaswamy, Vijay, Skowron, Patryk, Wölfl, Matthias, Milde, Till, Del Bigio, Marc R., Taylor, Michael D., Werbowetski‐Ogilvie, Tamra E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891039/
https://ncbi.nlm.nih.gov/pubmed/29377567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12177
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