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Activation of TNF‐α/NF‐κB axis enhances CRL4B(DCAF) (11) E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells

Cullin 4B, a member of the Cullins, which serve as scaffolds to facilitate the assembly of E3 ligase complexes, is aberrantly expressed in many cancers, including osteosarcoma. Recently, we observed that CUL4B forms the CRL4B(DCAF) (11) E3 ligase, which specifically ubiquitinates and degrades the cy...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Zhang, Caiguo, Chen, Bin, Jiang, Kaibiao, Lao, Lifeng, Shen, Hongxing, Chen, Zhi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891038/
https://ncbi.nlm.nih.gov/pubmed/29377600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12176
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