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Autoimmunity associated with chemically induced thymic dysplasia
Autoimmune and inflammatory conditions are frequent complications in patients with reduced numbers of T cells. Here, we describe a mouse model of thymic stromal dysplasia resulting in peripheral T-cell lymphopenia. In Foxn1:CFP-NTR transgenic mice, the bacterial nitroreductase enzyme is expressed in...
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| Veröffentlicht in: | Int Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890891/ https://ncbi.nlm.nih.gov/pubmed/28992076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxx048 |
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