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Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids

Chronic exposure to stress during midlife associates with subsequent age-related cognitive decline and may increase the vulnerability to develop psychiatric conditions. Increased hypothalamic-pituitary-adrenal (HPA) axis activity has been implicated in pathogenesis though any causative role for gluc...

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Detalhes bibliográficos
Publicado no:Psychoneuroendocrinology
Main Authors: Wheelan, Nicola, Kenyon, Christopher J., Harris, Anjanette P., Cairns, Carolynn, Al Dujaili, Emad, Seckl, Jonathan R., Yau, Joyce L.W.
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890827/
https://ncbi.nlm.nih.gov/pubmed/29306773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2017.12.018
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