Robust Graft Survival and Normalized Dopaminergic Innervation Do Not Obligate Recovery in a Parkinson Disease Patient

OBJECTIVE: The main goal of dopamine cell replacement therapy in Parkinson disease (PD) is to provide clinical benefit mediated by graft survival with nigrostriatal reinnervation. We report a dichotomy between graft structure and clinical function in a patient dying 16 years following fetal nigral g...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Neurol
Prif Awduron: Kordower, Jeffrey H., Goetz, Christopher G., Chu, Yaping, Halliday, Glenda M., Nicholson, Daniel A., Musial, Timothy F., Marmion, David J., Stoessl, A. Jon, Sossi, Vesna, Freeman, Thomas B., Olanow, C. Warren
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890810/
https://ncbi.nlm.nih.gov/pubmed/27900791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24820
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