Robust Graft Survival and Normalized Dopaminergic Innervation Do Not Obligate Recovery in a Parkinson Disease Patient

OBJECTIVE: The main goal of dopamine cell replacement therapy in Parkinson disease (PD) is to provide clinical benefit mediated by graft survival with nigrostriatal reinnervation. We report a dichotomy between graft structure and clinical function in a patient dying 16 years following fetal nigral g...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Kordower, Jeffrey H., Goetz, Christopher G., Chu, Yaping, Halliday, Glenda M., Nicholson, Daniel A., Musial, Timothy F., Marmion, David J., Stoessl, A. Jon, Sossi, Vesna, Freeman, Thomas B., Olanow, C. Warren
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890810/
https://ncbi.nlm.nih.gov/pubmed/27900791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24820
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