Robust Graft Survival and Normalized Dopaminergic Innervation Do Not Obligate Recovery in a Parkinson Disease Patient

OBJECTIVE: The main goal of dopamine cell replacement therapy in Parkinson disease (PD) is to provide clinical benefit mediated by graft survival with nigrostriatal reinnervation. We report a dichotomy between graft structure and clinical function in a patient dying 16 years following fetal nigral g...

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Bibliografski detalji
Izdano u:Ann Neurol
Glavni autori: Kordower, Jeffrey H., Goetz, Christopher G., Chu, Yaping, Halliday, Glenda M., Nicholson, Daniel A., Musial, Timothy F., Marmion, David J., Stoessl, A. Jon, Sossi, Vesna, Freeman, Thomas B., Olanow, C. Warren
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890810/
https://ncbi.nlm.nih.gov/pubmed/27900791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24820
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