A carregar...

A densely modified M(2+)-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover

Sequence-specific cleavage of RNA targets in the absence of a divalent metal cation (M(2+)) has been a long-standing goal in bioorganic chemistry. Herein, we report the in vitro selection of novel RNA cleaving DNAzymes that are selected using 8-histaminyl-deoxyadenosine (dA(im)TP), 5-guanidinoallyl-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wang, Yajun, Liu, Erkai, Lam, Curtis H., Perrin, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890787/
https://ncbi.nlm.nih.gov/pubmed/29675226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04491g
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!