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An Efficient Catalytic DNA that Cleaves L-RNA

Many DNAzymes have been isolated from synthetic DNA pools to cleave natural RNA (D-RNA) substrates and some have been utilized for the design of aptazyme biosensors for bioanalytical applications. Even though these biosensors perform well in simple sample matrices, they do not function effectively i...

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Publicat a:PLoS One
Autors principals: Tram, Kha, Xia, Jiaji, Gysbers, Rachel, Li, Yingfu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422682/
https://ncbi.nlm.nih.gov/pubmed/25946137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126402
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