Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells

OBJECTIVES: To characterize NAI-107 and related lantibiotics for their in vitro activity against Gram-negative pathogens, alone or in combination with polymyxin, and against non-dividing cells or biofilms of Staphylococcus aureus. NAI-107 was also evaluated for its propensity to select or induce sel...

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Bibliografiske detaljer
Udgivet i:J Antimicrob Chemother
Main Authors: Brunati, Cristina, Thomsen, Thomas T, Gaspari, Eleonora, Maffioli, Sonia, Sosio, Margherita, Jabes, Daniela, Løbner-Olesen, Anders, Donadio, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890740/
https://ncbi.nlm.nih.gov/pubmed/29092042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx395
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