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Pharmacological Properties of NAI-603, a Well-Tolerated Semisynthetic Derivative of Ramoplanin
NAI-603 is a ramoplanin derivative designed to overcome the tolerability issues of the parent drug as a systemic agent. NAI-603 is highly active against aerobic and anaerobic Gram-positive bacteria, with MICs ranging from 0.008 to 8 μg/ml. MICs were not significantly affected by pH (range, 6 to 8),...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023767/ https://ncbi.nlm.nih.gov/pubmed/24419352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01620-13 |
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