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Spatiotemporal pharmacodynamics of meropenem- and tobramycin-treated Pseudomonas aeruginosa biofilms

OBJECTIVES: The selection and dose of antibiotic therapy for biofilm-related infections are based on traditional pharmacokinetic studies using planktonic bacteria. The objective of this study was to characterize the time course and spatial activity of human exposure levels of meropenem and tobramyci...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Haagensen, Janus, Verotta, Davide, Huang, Liusheng, Engel, Joanne, Spormann, Alfred M, Yang, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890705/
https://ncbi.nlm.nih.gov/pubmed/28961810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx288
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