Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study

BACKGROUND: Moxifloxacin is a second-line anti-TB drug that is useful in the treatment of drug-resistant TB. However, little is known about its target site pharmacokinetics. Lower drug concentrations at the infection site (i.e. in severe lung lesions including cavitary lesions) may lead to developme...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Heinrichs, M Tobias, Vashakidze, Sergo, Nikolaishvili, Ketino, Sabulua, Irina, Tukvadze, Nestani, Bablishvili, Nino, Gogishvili, Shota, Little, Brent P, Bernheim, Adam, Guarner, Jeannette, Peloquin, Charles A, Blumberg, Henry M, Derendorf, Hartmut, Kempker, Russell R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890684/
https://ncbi.nlm.nih.gov/pubmed/29186509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx421
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