Cavitary Penetration of Levofloxacin among Patients with Multidrug-Resistant Tuberculosis

A better understanding of second-line drug (SLD) pharmacokinetics, including cavitary penetration, may help optimize SLD dosing. Patients with pulmonary multidrug-resistant tuberculosis (MDR-TB) undergoing adjunctive surgery were enrolled in Tbilisi, Georgia. Serum was obtained at 0, 1, 4, and 8 h a...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Kempker, Russell R., Barth, Aline B., Vashakidze, Sergo, Nikolaishvili, Ketino, Sabulua, Irina, Tukvadze, Nestani, Bablishvili, Nino, Gogishvili, Shota, Singh, Ravi Shankar P., Guarner, Jeannette, Derendorf, Hartmut, Peloquin, Charles A., Blumberg, Henry M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Clinical Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432208/
https://ncbi.nlm.nih.gov/pubmed/25779583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00379-15
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