Cavitary Penetration of Levofloxacin among Patients with Multidrug-Resistant Tuberculosis

A better understanding of second-line drug (SLD) pharmacokinetics, including cavitary penetration, may help optimize SLD dosing. Patients with pulmonary multidrug-resistant tuberculosis (MDR-TB) undergoing adjunctive surgery were enrolled in Tbilisi, Georgia. Serum was obtained at 0, 1, 4, and 8 h a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kempker, Russell R., Barth, Aline B., Vashakidze, Sergo, Nikolaishvili, Ketino, Sabulua, Irina, Tukvadze, Nestani, Bablishvili, Nino, Gogishvili, Shota, Singh, Ravi Shankar P., Guarner, Jeannette, Derendorf, Hartmut, Peloquin, Charles A., Blumberg, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432208/
https://ncbi.nlm.nih.gov/pubmed/25779583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00379-15
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