Detection of Methylation on dsDNA using Nanopores in MoS(2) Membrane

Methylation at the 5-carbon position of the cytosine nucleotide base in DNA has been shown to be a precursor to carcinogenesis. Early detection of methylation and intervention could drastically increase the effectiveness of therapy and reduce the cancer mortality rate. Current methods for detecting...

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Udgivet i:Nanoscale
Main Authors: Shim, Jiwook, Banerjee, Shouvik, Qiu, Hu, Smithe, Kirby K. H., Estrada, David, Bello, Julian, Pop, Eric, Schulten, Klaus, Bashir, Rashid
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890527/
https://ncbi.nlm.nih.gov/pubmed/28795735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7nr03092d
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