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Detection of Methylation on dsDNA using Nanopores in MoS(2) Membrane

Methylation at the 5-carbon position of the cytosine nucleotide base in DNA has been shown to be a precursor to carcinogenesis. Early detection of methylation and intervention could drastically increase the effectiveness of therapy and reduce the cancer mortality rate. Current methods for detecting...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nanoscale
Prif Awduron: Shim, Jiwook, Banerjee, Shouvik, Qiu, Hu, Smithe, Kirby K. H., Estrada, David, Bello, Julian, Pop, Eric, Schulten, Klaus, Bashir, Rashid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890527/
https://ncbi.nlm.nih.gov/pubmed/28795735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7nr03092d
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