Comparison of Two Molecular Assays for Detection and Characterization of Aspergillus fumigatus Triazole Resistance and Cyp51A Mutations in Clinical Isolates and Primary Clinical Samples of Immunocompromised Patients

In hematological patients, the incidence of invasive aspergillosis (IA) caused by azole resistant Aspergillus fumigatus (ARAf) is rising. As the diagnosis of IA is rarely based on positive culture in this group of patients, molecular detection of resistance mutations directly from clinical samples i...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Postina, Patricia, Skladny, Julian, Boch, Tobias, Cornely, Oliver A., Hamprecht, Axel, Rath, Peter-Michael, Steinmann, Jörg, Bader, Oliver, Miethke, Thomas, Dietz, Anne, Merker, Natalia, Hofmann, Wolf-Karsten, Buchheidt, Dieter, Spiess, Birgit
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890139/
https://ncbi.nlm.nih.gov/pubmed/29662479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00555
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