cyp51A-Based Mechanisms of Aspergillus fumigatus Azole Drug Resistance Present in Clinical Samples from Germany

Since the mid-1990s, a steady increase in the occurrence of itraconazole-resistant Aspergillus fumigatus isolates has been observed in clinical contexts, leading to therapeutic failure in the treatment of aspergillosis. This increase has been predominantly linked to a single allele of the cyp51A gen...

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Autores principales: Bader, Oliver, Weig, Michael, Reichard, Utz, Lugert, Raimond, Kuhns, Martin, Christner, Martin, Held, Jürgen, Peter, Silke, Schumacher, Ulrike, Buchheidt, Dieter, Tintelnot, Kathrin, Groß, Uwe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Epidemiology and Surveillance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719746/
https://ncbi.nlm.nih.gov/pubmed/23669382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00167-13
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