Development of Novel PCR Assays To Detect Azole Resistance-Mediating Mutations of the Aspergillus fumigatus cyp51A Gene in Primary Clinical Samples from Neutropenic Patients

The increasing incidence of azole resistance in Aspergillus fumigatus causing invasive aspergillosis (IA) in immunocompromised/hematological patients emphasizes the need to improve the detection of resistance-mediating cyp51A gene mutations from primary clinical samples, particularly as the diagnosi...

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Detalhes bibliográficos
Main Authors: Spiess, Birgit, Seifarth, Wolfgang, Merker, Natalia, Howard, Susan J., Reinwald, Mark, Dietz, Anne, Hofmann, Wolf-Karsten, Buchheidt, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393401/
https://ncbi.nlm.nih.gov/pubmed/22526309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05902-11
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