Effects of nicotine-containing and “nicotine-free” e-cigarette refill liquids on intracranial self-stimulation in rats

BACKGROUND: Animal models are needed to inform FDA regulation of electronic cigarettes (ECs) because they avoid limitations associated with human studies. We previously reported that an EC refill liquid produced less aversive/anhedonic effects at a high nicotine dose than nicotine alone as measured...

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Udgivet i:Drug Alcohol Depend
Main Authors: Harris, Andrew C., Muelken, Peter, Smethells, John R., Yershova, Katrina, Stepanov, Irina, Olson, Thao Tran, Kellar, Kenneth J., LeSage, Mark G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889751/
https://ncbi.nlm.nih.gov/pubmed/29413432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2017.11.032
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