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Coordination to lanthanide ions distorts binding site conformation in calmodulin

The Ca(2+)-sensing protein calmodulin (CaM) is a popular model of biological ion binding since it is both experimentally tractable and essential to survival in all eukaryotic cells. CaM modulates hundreds of target proteins and is sensitive to complex patterns of Ca(2+) exposure, indicating that it...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Edington, Sean C., Gonzalez, Andrea, Middendorf, Thomas R., Halling, D. Brent, Aldrich, Richard W., Baiz, Carlos R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889669/
https://ncbi.nlm.nih.gov/pubmed/29545272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722042115
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