Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control

BACKGROUND: Over 100 mammalian G protein-coupled receptors are yet to be matched with endogenous ligands; these so-called orphans are prospective drug targets for the treatment of disease. GPR37L1 is one such orphan, abundant in the brain and detectable as mRNA in the heart and kidney. GPR37L1 ablat...

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Publicado en:Biol Sex Differ
Autores principales: Coleman, James L. J., Mouat, Margaret A., Wu, Jianxin, Jancovski, Nikola, Bassi, Jaspreet K., Chan, Andrea Y., Humphreys, David T., Mrad, Nadine, Yu, Ze-Yan, Ngo, Tony, Iismaa, Siiri, dos Remedios, Cristobal G., Feneley, Michael P., Allen, Andrew M., Graham, Robert M., Smith, Nicola J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889568/
https://ncbi.nlm.nih.gov/pubmed/29625592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-018-0173-y
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