Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control

BACKGROUND: Over 100 mammalian G protein-coupled receptors are yet to be matched with endogenous ligands; these so-called orphans are prospective drug targets for the treatment of disease. GPR37L1 is one such orphan, abundant in the brain and detectable as mRNA in the heart and kidney. GPR37L1 ablat...

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Publicat a:Biol Sex Differ
Autors principals: Coleman, James L. J., Mouat, Margaret A., Wu, Jianxin, Jancovski, Nikola, Bassi, Jaspreet K., Chan, Andrea Y., Humphreys, David T., Mrad, Nadine, Yu, Ze-Yan, Ngo, Tony, Iismaa, Siiri, dos Remedios, Cristobal G., Feneley, Michael P., Allen, Andrew M., Graham, Robert M., Smith, Nicola J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889568/
https://ncbi.nlm.nih.gov/pubmed/29625592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-018-0173-y
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