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Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1

Orphan G protein-coupled receptors (GPCRs) represent a largely untapped resource for the treatment of a variety of diseases, despite sophisticated advances in drug discovery. Two promising orphan GPCRs are the endothelin B receptor-like proteins, GPR37 [ET(B)R-LP, Pael-R] and GPR37L1 [ET(B)R-LP-2]....

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Autor principal: Smith, Nicola J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648071/
https://ncbi.nlm.nih.gov/pubmed/26635605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00275
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