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Stress promotes drug seeking through glucocorticoid-dependent endocannabinoid mobilization in prelimbic cortex

BACKGROUND: Clinical reports suggest that, rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “set the stage” for relapse by promoting endocannabi...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: McReynolds, Jayme R., Doncheck, Elizabeth M., Li, Yan, Vranjkovic, Oliver, Graf, Evan N., Ogasawara, Daisuke, Cravatt, Benjamin F., Baker, David A., Liu, Qing-song, Hillard, Cecilia J., Mantsch, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889367/
https://ncbi.nlm.nih.gov/pubmed/29100630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.09.024
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