17β-Estradiol Potentiates the Reinstatement of Cocaine Seeking in Female Rats: Role of the Prelimbic Prefrontal Cortex and Cannabinoid Type-1 Receptors

Clinical observations imply that female cocaine addicts experience enhanced relapse vulnerability compared with males, an effect tied to elevated estrogen phases of the ovarian hormone cycle. Although estrogens can enhance drug-seeking behavior, they do not directly induce reinstatement on their own...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Doncheck, Elizabeth M, Urbanik, Luke A, DeBaker, Margot C, Barron, Laura M, Liddiard, Gage T, Tuscher, Jennifer J, Frick, Karyn M, Hillard, Cecilia J, Mantsch, John R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809785/
https://ncbi.nlm.nih.gov/pubmed/28825421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.170
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