CB1 receptor antagonism blocks stress-potentiated reinstatement of cocaine seeking in rats

RATIONALE: Under some conditions stress, rather than directly triggering cocaine seeking, potentiates reinstatement to other stimuli, including a sub-threshold cocaine dose. The mechanisms responsible for stress-potentiated reinstatement are not well-defined. Endocannabinoid signaling is increased b...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: McReynolds, Jayme R., Doncheck, Elizabeth M., Vranjkovic, Oliver, Ganzman, Geoffrey S., Baker, David A., Hillard, Cecilia J., Mantsch, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703460/
https://ncbi.nlm.nih.gov/pubmed/26455361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-4092-x
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