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Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats

Stress-induced reinstatement of cocaine seeking requires corticotropin releasing factor (CRF) actions in the ventral tegmental area (VTA). However the mechanisms through which CRF regulates VTA function to promote cocaine use are not fully understood. Here we examined the role of GABAergic neurotran...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Blacktop, Jordan M., Vranjkovic, Oliver, Mayer, Matthieu, Van Hoof, Matthew, Baker, David A., Mantsch, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717150/
https://ncbi.nlm.nih.gov/pubmed/26596556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.11.013
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