Multiple system atrophy and apolipoprotein E

OBJECTIVE: This study evaluated genetic associations of APOE alleles with risk of MSA and α-synuclein pathology, and also examined whether apoE isoforms differentially affect α-synuclein uptake in oligodendrocytes cell. METHODS: 168 pathologically-confirmed MSA patients, 89 clinically-diagnosed MSA...

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Publicat a:Mov Disord
Autors principals: Ogaki, Kotaro, Martens, Yuka A., Heckman, Michael G., Koga, Shunsuke, Labbé, Catherine, Lorenzo-Betancor, Oswaldo, Wernick, Anna I., Walton, Ronald L., Soto, Alexandra I., Vargas, Emily R., Nielsen, Henrietta M., Fujioka, Shinsuke, Kanekiyo, Takahisa, Uitti, Ryan J., van Gerpen, Jay A., Cheshire, William P., Wszolek, Zbigniew K., Low, Phillip A., Singer, Wolfgang, Dickson, Dennis W., Bu, Guojun, Ross, Owen A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889322/
https://ncbi.nlm.nih.gov/pubmed/29442376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27297
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