Multiple system atrophy and apolipoprotein E

OBJECTIVE: This study evaluated genetic associations of APOE alleles with risk of MSA and α-synuclein pathology, and also examined whether apoE isoforms differentially affect α-synuclein uptake in oligodendrocytes cell. METHODS: 168 pathologically-confirmed MSA patients, 89 clinically-diagnosed MSA...

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Pubblicato in:Mov Disord
Autori principali: Ogaki, Kotaro, Martens, Yuka A., Heckman, Michael G., Koga, Shunsuke, Labbé, Catherine, Lorenzo-Betancor, Oswaldo, Wernick, Anna I., Walton, Ronald L., Soto, Alexandra I., Vargas, Emily R., Nielsen, Henrietta M., Fujioka, Shinsuke, Kanekiyo, Takahisa, Uitti, Ryan J., van Gerpen, Jay A., Cheshire, William P., Wszolek, Zbigniew K., Low, Phillip A., Singer, Wolfgang, Dickson, Dennis W., Bu, Guojun, Ross, Owen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889322/
https://ncbi.nlm.nih.gov/pubmed/29442376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27297
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