Multiple system atrophy and apolipoprotein E

OBJECTIVE: This study evaluated genetic associations of APOE alleles with risk of MSA and α-synuclein pathology, and also examined whether apoE isoforms differentially affect α-synuclein uptake in oligodendrocytes cell. METHODS: 168 pathologically-confirmed MSA patients, 89 clinically-diagnosed MSA...

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Détails bibliographiques
Publié dans:Mov Disord
Auteurs principaux: Ogaki, Kotaro, Martens, Yuka A., Heckman, Michael G., Koga, Shunsuke, Labbé, Catherine, Lorenzo-Betancor, Oswaldo, Wernick, Anna I., Walton, Ronald L., Soto, Alexandra I., Vargas, Emily R., Nielsen, Henrietta M., Fujioka, Shinsuke, Kanekiyo, Takahisa, Uitti, Ryan J., van Gerpen, Jay A., Cheshire, William P., Wszolek, Zbigniew K., Low, Phillip A., Singer, Wolfgang, Dickson, Dennis W., Bu, Guojun, Ross, Owen A.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889322/
https://ncbi.nlm.nih.gov/pubmed/29442376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27297
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