Amylin and Diabetic Cardiomyopathy – Amylin-Induced Sarcolemmal Ca(2+) Leak Is Independent of Diabetic Remodeling of Myocardium

Amylin is a pancreatic β-cell hormone co-secreted with insulin, plays a role in normal glucose homeostasis, and forms amyloid in the pancreatic islets of individuals with type-2 diabetes. Aggregated amylin is also found in blood and extra-pancreatic tissues, including myocardium. Myocardial amylin a...

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Bibliografiske detaljer
Udgivet i:	Biochim Biophys Acta
Main Authors:	Liu, Miao, Hoskins, Amanda, Verma, Nirmal, Bers, Donald M, Despa, Sanda, Despa, Florin
Format:	Artigo
Sprog:	Inglês
Udgivet:	2017
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5889317/ https://ncbi.nlm.nih.gov/pubmed/29066284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.10.024
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Amylin and Diabetic Cardiomyopathy – Amylin-Induced Sarcolemmal Ca(2+) Leak Is Independent of Diabetic Remodeling of Myocardium

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