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Amylin and Diabetic Cardiomyopathy – Amylin-Induced Sarcolemmal Ca(2+) Leak Is Independent of Diabetic Remodeling of Myocardium
Amylin is a pancreatic β-cell hormone co-secreted with insulin, plays a role in normal glucose homeostasis, and forms amyloid in the pancreatic islets of individuals with type-2 diabetes. Aggregated amylin is also found in blood and extra-pancreatic tissues, including myocardium. Myocardial amylin a...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889317/ https://ncbi.nlm.nih.gov/pubmed/29066284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.10.024 |
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