Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury

Hypersecretion of amylin is common in individuals with prediabetes, causes amylin deposition and proteotoxicity in pancreatic islets, and contributes to the development of type 2 diabetes. Recent studies also identified amylin deposits in failing hearts from patients with obesity or type 2 diabetes...

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Vydáno v:Diabetes
Hlavní autoři: Liu, Miao, Verma, Nirmal, Peng, Xiaoli, Srodulski, Sarah, Morris, Andrew, Chow, Martin, Hersh, Louis B., Chen, Jing, Zhu, Haining, Netea, Mihai G., Margulies, Kenneth B., Despa, Sanda, Despa, Florin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2016
Témata:
Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001184/
https://ncbi.nlm.nih.gov/pubmed/27335231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0044
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