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Programmable RNA cleavage and recognition by a natural CRISPR-Cas9 system from Neisseria meningitidis
The microbial CRISPR systems enable adaptive defense against mobile elements, and also provide formidable tools for genome engineering. The Cas9 proteins are Type II CRISPR-associated, RNA-guided DNA endonucleases that identify double-stranded DNA targets by sequence complementarity and protospacer...
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| 出版年: | Mol Cell |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889306/ https://ncbi.nlm.nih.gov/pubmed/29456189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.025 |
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