Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is considered as an immunosuppressive disease, with impaired tumor-infiltrating T lymphocytes and increased suppressive immune cells. The efficacy of CD47 antibodies in immune checkpoint therapy is not clearly understood in HNSCC. In this study, human ti...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Wu, Lei, Yu, Guang-Tao, Deng, Wei-Wei, Mao, Liang, Yang, Lei-Lei, Ma, Si-Rui, Bu, Lin-Lin, Kulkarni, Ashok B., Zhang, Wen-Feng, Zhang, Lu, Sun, Zhi-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889284/
https://ncbi.nlm.nih.gov/pubmed/29632717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1397248
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