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HLA ligandome analysis of primary chronic lymphocytic leukemia (CLL) cells under lenalidomide treatment confirms the suitability of lenalidomide for combination with T-cell-based immunotherapy

Recent studies suggest that CLL is an immunogenic disease, which might be effectively targeted by antigen-specific T-cell-based immunotherapy. However, CLL is associated with a profound immune defect, which might represent a critical limitation for mounting clinically effective antitumor immune resp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Nelde, Annika, Kowalewski, Daniel J., Backert, Linus, Schuster, Heiko, Werner, Jan-Ole, Klein, Reinhild, Kohlbacher, Oliver, Kanz, Lothar, Salih, Helmut R., Rammensee, Hans-Georg, Stevanović, Stefan, Walz, Juliane S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889201/
https://ncbi.nlm.nih.gov/pubmed/29632711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1316438
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