Mapping the HLA-ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation

Immune cell infiltrates have proven highly relevant for colorectal carcinoma (CRC) prognosis, making CRC a promising candidate for immunotherapy. Since tumors interact with the immune system via HLA-presented peptide ligands, exact knowledge of the peptidome constitution is fundamental for understan...

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Bibliografische gegevens
Gepubliceerd in:Cancer Res
Hoofdauteurs: Löffler, Markus W., Kowalewski, Daniel J., Backert, Linus, Bernhardt, Jörg, Adam, Patrick, Schuster, Heiko, Dengler, Florian, Backes, Daniel, Kopp, Hans-Georg, Beckert, Stefan, Wagner, Silvia, Königsrainer, Ingmar, Kohlbacher, Oliver, Kanz, Lothar, Königsrainer, Alfred, Rammensee, Hans-Georg, Stevanović, Stefan, Haen, Sebastian P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235106/
https://ncbi.nlm.nih.gov/pubmed/29789417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1745
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