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HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL)

The breakthrough development of clinically effective immune checkpoint inhibitors illustrates the potential of T-cell–based immunotherapy to effectively treat malignancies. A remaining challenge is to increase and guide the specificities of anticancer immune responses, e.g., by therapeutic vaccinati...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kowalewski, Daniel J., Schuster, Heiko, Backert, Linus, Berlin, Claudia, Kahn, Stefan, Kanz, Lothar, Salih, Helmut R., Rammensee, Hans-Georg, Stevanovic, Stefan, Stickel, Juliane Sarah
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299203/
https://ncbi.nlm.nih.gov/pubmed/25548167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416389112
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