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PIKfyve regulates melanosome biogenesis
PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P(2), a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that lead to both neurodegeneration and coat color defe...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889185/ https://ncbi.nlm.nih.gov/pubmed/29584722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007290 |
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