PIKfyve regulates melanosome biogenesis

PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P(2), a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that lead to both neurodegeneration and coat color defe...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Liggins, Marc C., Flesher, Jessica L., Jahid, Sohail, Vasudeva, Priya, Eby, Victoria, Takasuga, Shunsuke, Sasaki, Junko, Sasaki, Takehiko, Boissy, Raymond E., Ganesan, Anand K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889185/
https://ncbi.nlm.nih.gov/pubmed/29584722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007290
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