PIKfyve regulates melanosome biogenesis

PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P(2), a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that lead to both neurodegeneration and coat color defe...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Liggins, Marc C., Flesher, Jessica L., Jahid, Sohail, Vasudeva, Priya, Eby, Victoria, Takasuga, Shunsuke, Sasaki, Junko, Sasaki, Takehiko, Boissy, Raymond E., Ganesan, Anand K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889185/
https://ncbi.nlm.nih.gov/pubmed/29584722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007290
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